For a middle-aged woman with no comorbidities (decile 5) admitted to the ICU with pneumonia, her chance of dying in the hospital is 4.55 (99% CI, 3.24-6.38) times greater if she has 2 or more SOFA points compared with less than 2 SOFA points. Panel A, Interpretive example: the x-axis divides the cohort into deciles of baseline mortality risk, determined by all available information at the time of ICU admission including factors relating to the ICU (size, type, location, and admission source), admission time (month, day, and hour) and patient (age, sex, comorbidities, pregnancy, diabetes, indigenous status, and treatment limitations). Data referenced against the model of baseline risk of in-hospital mortality (Panel A) and baseline risk of in-hospital mortality or ICU length of stay ≥3 days (Panel B) determined for the cohort, based on variables independent of the scoring systems (data available in eTables 1-2 in the Supplement). ICU indicates intensive care unit qSOFA, quick Sequential Organ Function Assessment SIRS, systemic inflammatory response syndrome SOFA, Sequential Organ Function Assessment.
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